Pharmaceutical Drug Injury: Bisphosphonates - Fosamax

Fosamax


Bisphosphonate :: Osteonecrosis :: ONJ :: Jaw Necrosis
Bis-Phossy Jaw ::Phossy Jaw :: Fossy Jaw
Dead Jaw :: Femur Fracture

Fosamax® (alendronate sodium), is a bisphosphonate drug medication manufactured by Merck and is used to treat osteoporosis.

FDA Review - Bisphosphonates

On August 25, 2004, the FDA released the results of its ODS Postmarketing Safety Review of various bisphosphonates, incuding Aredia (pamidronate) and Zometa (zoledronic acid), Fosamax (alendronate), Actonel (risedronate). In this report, the FDA recommended that language be added to the labels of some bisphosphonate drugs in order to advise of the risk of osteonecrosis.

Health Concerns

Some bisphosponates drugs like Fosamax may have certain side effects or problems that may cause a painful and disfiguring condition referred to as Osteonecrosis. Osteonecrosis causes the jaw bone to decay and die (which may cause problems with your teeth and jaw).

Merck, the manufacturer of Fosamax, may have failed to warn users of a possible side effect or problem from using the drug Fosamax. Possible side effects may include Osteonecrosis (also know as ONJ, Jaw Necrosis, Bis-Phossy Jaw, Phossy Jaw, Fossy Jaw or Dead Jaw) and/or femur fracture problems.

Bisphosphonates - e.g., Fosamax -
Medical Studies/Information

Jaw Problems

Recently, January 9, 2009, the USC School of Dentistry stated that "Even short-term use of common oral osteoporosis drugs may leave the jaw vulnerable to devastating necrosis," according to a new USC School of Dentistry study appearing in the January 1, 2009 Journal of the American Dental Association (JADA).

For more on Fosamax cases, please follow this link.


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